ABSTRACT
COVID-19 affects pregnant women more severely than nonpregnant women of reproductive age. However, the rate of critical illness and fatality reported in other studies varied in a wide range in both groups. The study aims to investigate the clinical outcomes of COVID-19 in the pregnant and nonpregnant matched control patients admitted to the hospital. Pregnant and nonpregnant patients of reproductive age (18-45 years) infected with COVID-19 who were admitted to Ondokuz Mayis University Hospital, Samsun, Turkey, from March 11 to December 11, 2020, were enrolled in the study. The clinical, radiological, and laboratory data of the patients were analyzed retrospectively. A total of 153 patients were investigated;123 were nonpregnant, and 30 were pregnant. Emergency delivery occurred in 5 (17%) pregnant women due to acute respiratory failure associated with COVID-19 and 1 (3%) pregnant woman due to obstetric reasons. Four premature births, one perinatal death, and no stillbirth or miscarriage were reported. The rate of admission to the intensive care unit (ICU) [7/30 (23.3%) vs 3/123 (2.4%), p<0.001] and the need for invasive mechanical ventilation (IMV) [5/30 (17.0%) vs 2/123 (1.6%), p=0.003] were significantly higher in pregnant than in non-pregnant patients. However, hospital length of stay (HLOS) and mortality did not differ between groups: HLOS was median 4 vs 5 days, p=0.68, and the mortality rate was 1/123 (0.8%) vs 0/30 (0%), p=0.62 in nonpregnant and pregnant patients respectively. We observed that COVID-19 has a more severe course in pregnant women versus the nonpregnant control group, but no difference was noted in terms of hospital length of stay and mortality. The overall case fatality rate of COVID-19 in hospitalized pregnant or nonpregnant women of reproductive age was found to be much lower than the general hospitalized population worldwide. Copyright © 2022 Ondokuz Mayis Universitesi. All rights reserved.
ABSTRACT
There are very few reports on the prevalence of multidrug-resistant microorganisms during the COVID-19 pandemic. In addition, these publications usually cover covid-19 patients.Our study aimed to compare the prevalence of multidrug-resistant microorganisms in patients without COVID-19 undergoing treatment in an intensive care unit (ICU) during the COVID-19 pandemic with those in the pre-pandemic period. The study was planned retrospectively. In our country, the prevalence of multi-drug-resistant microorganisms was evaluated in the intensive care unit where internal and surgical patients were hospitalized in a single center in 6-month periods before and after the occurrence of covid-19 cases. The prevalence of multidrug-resistant microorganisms increased in patients being followed up in our ICU during the pandemic period (p<0.05). Statistically significant relationships were found between the incidence rate of microorganisms with multi-drug resistance and sex (p=0.028), presence of malignancy (p=0.011), and nurse's duration of work in the ICU (p=0.04). The increased prevalence of multidrug-resistant microorganisms and the infections caused by these microorganisms are other challenges that must be tackled during the pandemic period.
ABSTRACT
This paper investigates the foremost firm-specific factors having an impact on financial distress and bankruptcy in the acute stage of the Covid-19 crisis based on data from approximately 9,000 enterprises in 25 countries. Empirical results of a random forest algorithm with SHAP values show increased odds of both bankruptcy and financial distress for firms that have problems in accessing finance, younger firms and more indebted firms. In addition, the size of the firm and the years of experience of its managers also have an impact on financial failure. However, country features are more important than firm features in predicting bankruptcy and financial distress in the Covid-19 crisis.